@Michelle Riggs honestly the coexistence situation on 2.4GHz is one of those things that can range from "barely noticeable" to "complete nightmare" depending on how you handle it, and the short answer is you're going to need to do some work on your end regardless.
The STM32WB07 at the heart of the MultiNav Pro+ does have some built-in coexistence signaling support — it can output PTA (Packet Traffic Arbitration) signals that let it coordinate with a WiFi chip, but whether that helps you depends entirely on whether your WiFi radio also supports PTA and whether you wire it up. If both radios support it and you connect them, they can take turns instead of stomping on each other. If not, you're relying on BLE's adaptive frequency hopping to dodge the WiFi channels, which works reasonably well for typical use but degrades when your WiFi is doing heavy throughput.
Physical separation is genuinely worth the effort on the PCB — keeping the two antenna traces and RF front-ends as far apart as practical, using ground pours between them, and making sure your antenna placement doesn't have them firing into each other will make a real difference before you even touch software. The external amplifiers on the MultiNav Pro+ give you excellent sensitivity, but that cuts both ways — a nearby interferer gets amplified too.
If you haven't already, it's worth checking the STM32WB07 application notes from ST on coexistence — they have some pretty specific guidance on PTA wiring and timing that maps directly to this chip. And if you want to share your board layout I'm happy to take a look at what you're working with.
